|
KMID : 0895820020120020007
|
|
Journal of Oriental Rehabilitation Medicine
2002 Volume.12 No. 2 p.7 ~ p.0
|
|
|
Effects of Full Spectrum Visible Ray Therapy by Carbon Electrodes on the Cutaneous Wound Healing of Rat
|
|
Song Jae-Chul
Lee Jong-Soo
Chung Seok-Hee
Kim Sung-Su
Shin Hyun-Dae
|
|
|
Abstract
|
|
|
Objectives: Our purpose was to evaluate the efficacy of Full Spectrum Visible Ray of carbon electrodes No. 3000 and No. 3002, No. 3001 and No. 4008 in the healing of full-thickness excision wound.
Methods: We used Sprague-Dawley rats of 8 weeks aged. They were divided three groups, one control group and two experimental groups. Full-thickness excision wound were made on the back of the all rats of each group. Full Spectrum Visible Ray of carbon electrodes, No. 3000 and No. 3002 were radiated to rats of one experimental group in 15 minutes a day for 2 weeks. Full Spectrum Visible Ray of carbon electrodes, No. 3001 and No. 4008 were radiated to rats of the other experimental group in 15 minutes a day for 2 weeks. The exicision wounds were examined intensely on the 1st, 2nd, 4th, 7th, 14th day after exicision. Morphological changes were examined in hematoxylin-eosin staining and azan staining. Epidermal growth factor, transforming growth factor β1, transforming growth factorβ3 were examined in immunohistochemical staining.
Results:
1. Full Spectrum Visible Ray of No. 3000 and 3002 carbon electrodes have effects to accelerate wound healing process.
2. Full Spectrum Visible Ray of No. 3001 and 4008 carbon electrodes have anti-inflammatory effects.
3. Transforming growth factor β1 and β3 have competitive inhibition actions.
Conclusions: These findings suggest that Full Spectrum Visible Ray of No. 3000 and 3002 carbon electrodes have accelerating effects on full-thickness exicision wound healing, and that Full Spectrum Visible Ray of No. 3001 and 4008 carbon electrodes have anti-inflammatory effects.
|
|
|
KEYWORD
|
|
|
Wound healing, Carbon electrode, Growth factor, Epidermal growth factor, Transforming growth factor β1, Transforming growth factor β3
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|
|